gPRA (crd3) is one of several cone rod dystrophies that have been recognized in multiple breeds of dogs.
All forms of CRD are characterized by the initial loss of cones, the cells in the retina that are responsible for vision in bright light/daylight, followed by the degeneration of rods, the retinal cells that operate during night vision.
crd3 is typically a late-onset disease. Clinical symptoms of crd3 are usually not evident until adulthood has been reached. The clinical appearance of crd3 is similar to other common forms of late-onset PRA, namely there is retinal thinning that can be observed by a veterinary ophthalmologist in dogs as young as 3 years of age and retinal degeneration progression, resulting in total blindness within a few years.
Gene Tested : ADAM9