Lupoid Dermatosis, also known as Exfoliative Cutaneous Lupus Erythematosus is a monogenic (controlled by one gene) autosomal recessive disease that has been described in German Shorthaired Pointers and Vizslas.
Clinical signs become apparent before one year of age. These clinical signs include skin lesions, lameness, scaling, erythema (reddening of the skin), erosions/ulcers, scarring, disfiguration, decreased quality of life, progresses to joint pain, oligospermia (low sperm count) in males which progressed to azoospermia (absence of sperm), irregular heat cycles in females.
Dogs with this disease have dramatically shortened life expectancies and are generally humanely euthanized upon diagnosis.