Hereditary Nephritis / Samoyed Hereditary Glomerulopathy

Hereditary nephritis / glomerulonephropathy in Samoyed is a recessive, X-linked hereditary disease that affects young male dogs more severely than females. Affected males and females spontaneously develop proteinuria, but only males progress to renal failure.

Affected male puppies usually show symptoms of the disease by 2 to 3 months of age. They start to lose weight noticeably and kidney function deteriorates rapidly, resulting in death by an early age (approximately 1 year).

Females who carry the disease also lose weight and develop proteinuria between two and three months of age, but the disease is less severe and does not progresses to kidney failure.

Possible Test Results :

• Clear
• Carrier
• Affected
• Hereditary Clear
• Hereditary Carrier
• Hereditary Affected