Imerslund-Grasbeck Syndrome (IGS) or Cobalamin Malabsorption is a disorder where dietary cobalamin (vitamin B12) is unable to be absorbed through the gut.
Owners of IGS affected dogs often note a lack of appetite, failure to gain weight, lethargy and malaise that intensifies after eating. Clinically, anemia and excess urine protein is observed. Without chronic treatment, permanent brain and nervous system damage can occur.