Progressive Retinal Atrophy (PRA3)

PRA3: The condition is characterised by bilateral degeneration of the retina which causes progressive vision loss that culminates in total blindness. There is no treatment for PRA, of which several genetically distinct forms are recognised, each caused by a different mutation in a specific gene.

The PRA3 mutation is recessive, meaning a dog needs to inherit two copies of the mutation to be clinically affected with PRA. PRA3 is a late-onset condition and clinical signs can usually be detected by an ophthalmologist from 4-7 years of age.

Possible Test Results :

• Clear
• Carrier
• Affected
• Hereditary Clear
• Hereditary Carrier
• Hereditary Affected

Progressive Retinal Atrophy (PRA3) is a mandatory test for the following breeds :

• Tibetan Spaniel
• Tibetan Terrier