Mucopolysaccharidosis type VII

Mucopolysaccharidosis type VII belongs to a group of rare genetic disorders of glycosaminglycan catabolism resulting in lysosomal storage. Clinical signs are corneal clouding and severe skeletal deformities. Affected dogs are unable to ambulate at several weeks to months of age. Mucopolysaccharidosis type VII is an inherited autosomal recessive trait. This means that a dog can be clear (homozygous normal), affected, or a carrier (heterozygous). The carriers can spread the diseased gene in the population. Therefore, reliable information on non-affected dogs is the key to controlling this disease.

Possible Test Results :

• Clear
• Carrier
• Affected
• Hereditary Clear
• Hereditary Carrier
• Hereditary Affected